The ADDit™ Additive Screen contains a set of 96 different small molecule and salt solutions that have been found to be effective in aiding the crystallization of biological macromolecules. It comprises a range of crystal growth promoters and nucleation suppressants including detergents, chelators, reducing agents, volatile and non-volatile organics, heavy atoms, and salts. The pHat™ Buffers comprise a multi-purpose 96 buffer kit of 12 different buffer systems at 8 different pHs, ranging from ±1.4 pH units about the buffer pKa. Apply these buffers to your protein crystallization hits to simultaneously explore the effects of pH and buffer composition on crystal growth